Penny Marshall, who starred alongside Cindy Williams in the hit ABC comedy “Laverne & Shirley” and then became a successful director, died on Monday night at her Hollywood Hills home due to complications from diabetes, Variety has confirmed. She was 75.

Marshall was the first woman to direct a film that grossed more than $100 million, the first woman to direct two films that made more than $100 million, and she was only the second woman director to see her film Oscar-nominated for best picture.

“Laverne & Shirley” ran from 1976-1983 and proved an enormous success for ABC. It was the No. 3 show on television in 1975-76, No. 2 in 1976-77, and No. 1 in 1977-78 and 1978-79, spawning ancillary revenue in the form of merchandising, a record album, and an animated series based on the show.